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|Section2= }} Neophyl chloride, C6H5C(CH3)2CH2Cl, is a halogenated organic compound with unusual nucleophilic substitution properties. Neophyl chloride is used to form a versatile organolithium reagent, neophyl lithium, by reaction with lithium.〔Lide, R. D.; ''CRC Handbook of Chemistry and Physics''. 2003, 590. ISBN 0-8493-0595-0〕〔Andrew Streitwieser and Clayton H. Heathcock. ''Introduction to Organic Chemistry''. 3rd ed. New York: Macmillan Co., 1985. ISBN 0-02-946720-9〕 == Preparation == Neophyl chloride was first synthesized by Haller and Ramart by reacting the chlorinating reagent thionyl chloride with neophyl alcohol: :C6H5C(CH3)2CH2OH + SOCl2 → C6H5C(CH3)2CH2Cl + HCl + SO2 It is easily prepared on a large scale by combining benzene and methallyl chloride in the presence of a catalytic quantity of sulfuric acid. The reaction is an example of an electrophilic aromatic substitution. :H2C=C(CH3)CH2Cl + C6H6 → C6H5C(CH3)2CH2Cl Alternatively ''tert''-butylbenzene can be chlorinated with sulfuryl chloride. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Neophyl chloride」の詳細全文を読む スポンサード リンク
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